中国3种不同地方品系鸡对马立克病毒超强毒株rMd5易感性比较

doi:10.11843/j.issn.0366-6964.2014.01.014

畜牧兽医学报 ›› 2014, Vol. 45 ›› Issue (1): 101-106.doi: 10.11843/j.issn.0366-6964.2014.01.014

中国3种不同地方品系鸡对马立克病毒超强毒株rMd5易感性比较

崔宁，苏帅，陈孜孟，赵孝民，崔治中^*

（山东农业大学动物科技学院, 泰安 271018）

收稿日期:2013-07-23 出版日期:2014-01-23 发布日期:2014-01-23
通讯作者: 崔治中，教授，E-mail: zzcui@sdau.edu.cn
作者简介:崔宁（1989- ），女，山东日照人,博士研究生,主要从事动物分子病毒学研究，E-mail:cnydia@163.com
基金资助:
国家自然科学基金（31072149）

Comparison of the Susceptibility of Three Different Local Chicken Lines in China to Very Virulent Strain rMd5

CUI Ning, SU Shuai, CHEN Zi-meng, ZHAO Xiao-min, CUI Zhi-zhong^*

(Animal Science and Technology College, Shandong Agricultural University, Taian 271018, China)

Received:2013-07-23 Online:2014-01-23 Published:2014-01-23

摘要/Abstract

摘要：

比较了马立克病毒超强毒株rMd5对中国3种不同地方品系鸡（济宁百日鸡、汶上芦花鸡、寿光黑鸡）的致病性。将rMd5分别腹腔接种1日龄（500 PFU·只^－¹）和7日龄（1 500 PFU·只^－¹）不同品系鸡并饲养90 d。结果表明rMd5均能够引起3种地方品系鸡的特异性马立克病变，但是致病性的强度差异显著：寿光黑鸡的死亡率和肿瘤发生率明显高于其他2种鸡，几乎和SPF鸡类似，而且rMd5在寿光黑鸡群中的横向传播能力最强；济宁百日鸡和汶上芦花鸡相比对rMd5的抗感染和抗病能力强。因此，济宁百日鸡和汶上芦花鸡可作为遗传抗性基因的筛选和遗传抗性机制研究的候选品系。

Abstract:

This experiment was conducted to study the pathogenicity of very virulent MDV strain rMd5 between three different local chicken lines (Ji-ning-bai-ri, Wen-shang-lu-hua, Shou-guang-hei) in China. rMd5 strain was inoculated to chickens by intraperitoneal injection, 1-day-old chicken with 500 PFU and 7-day-old chicken with 1 500 PFU. The feeding trial lasted for 90 days. rMd5 causes specific lesions of Marek’s disease in three different local chicken lines, but the degree of the pathogenicity differs significantly: the mortality and oncogenicity of Shou-guang-hei are significantly higher than the other two chicken lines, which is almost similar to SPF chicken. In addition, the transmission capacity of rMd5 in Shou-guang-hei is the highest; By contrast, the resistance of Ji-ning-bai-ri and Wen-shang-lu-hua lines to rMd5 infection and disease are greater. Therefore, Ji-ning-bai-ri and Wen-shang-lu-hua can be candidate lines to screen for genetic resistance genes and study genetic resistance mechanism.

中图分类号:

S852.659.1

崔宁，苏帅，陈孜孟，赵孝民，崔治中. 中国3种不同地方品系鸡对马立克病毒超强毒株rMd5易感性比较[J]. 畜牧兽医学报, 2014, 45(1): 101-106.

CUI Ning, SU Shuai, CHEN Zi-meng, ZHAO Xiao-min, CUI Zhi-zhong. Comparison of the Susceptibility of Three Different Local Chicken Lines in China to Very Virulent Strain rMd5[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(1): 101-106.

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中国3种不同地方品系鸡对马立克病毒超强毒株rMd5易感性比较

Comparison of the Susceptibility of Three Different Local Chicken Lines in China to Very Virulent Strain rMd5

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